Ontology highlight
ABSTRACT:
SUBMITTER: Masi LN
PROVIDER: S-EPMC7883809 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Masi Laureane N LN Lotufo Paulo A PA Ferreira Frederico M FM Rodrigues Alice C AC Serdan Tamires D A TDA Souza-Siqueira Talita T Braga Aécio A AA Saldarriaga Magda E G MEG Alba-Loureiro Tatiana C TC Borges Fernanda T FT Cury Diego P DP Hirata Mario H MH Gorjão Renata R Pithon-Curi Tania C TC Lottenberg Simão A SA Fedeli Ligia M G LMG Nakaya Helder T I HTI Bensenor Isabela J M IJM Curi Rui R Hirabara Sandro M SM
Physiological reports 20210201 3
We measured plasma-derived extracellular vesicle (EV) proteins and their microRNA (miRNA) cargos in normoglycemic (NG), glucose intolerant (GI), and newly diagnosed diabetes mellitus (DM) in middle-aged male participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil). Mass spectrometry revealed decreased IGHG-1 and increased ITIH2 protein levels in the GI group compared with that in the NG group and higher serotransferrin in EVs in the DM group than in those in the NG and GI g ...[more]