Whole genome phylogenies reflect the distributions of recombination rates for many bacterial species.
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ABSTRACT:
SUBMITTER: Sakoparnig T
PROVIDER: S-EPMC7884076 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Whole genome phylogenies reflect the distributions of recombination rates for many bacterial species.
Sakoparnig Thomas T Field Chris C van Nimwegen Erik E
eLife 20210108
Although recombination is accepted to be common in bacteria, for many species robust phylogenies with well-resolved branches can be reconstructed from whole genome alignments of strains, and these are generally interpreted to reflect clonal relationships. Using new methods based on the statistics of single-nucleotide polymorphism (SNP) splits, we show that this interpretation is incorrect. For many species, each locus has recombined many times along its line of descent, and instead of many loci ...[more]
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