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Ophthalmic manifestations associated with SARS-CoV-2 in newborn infants: a preliminary report.


ABSTRACT: COVID-19, caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), affects people of all ages. The virus can cause multiple systemic infections, principally in the respiratory tract, as well as microvascular damage. Ocular manifestations of COVID-19 are uncommon in adults and children. We describe ophthalmic manifestations in newborns detected by slit-lamp examination, fundus examination, and fluorescein angiography. All patients showed edema and hemorrhagic conjunctivitis; fundus examinations revealed cotton wool spots and vitreous hemorrhage, and microvascular damage manifested as patchy choroidal filling, peripapillary hyperfluorescence, delayed retinal filling and venous laminar flow, and boxcarring on fluorescein angiography.

SUBMITTER: Perez-Chimal LG 

PROVIDER: S-EPMC7884229 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Ophthalmic manifestations associated with SARS-CoV-2 in newborn infants: a preliminary report.

Pérez-Chimal Luis Gilberto LG   Cuevas Gabriela García GG   Di-Luciano Andreas A   Chamartín Pablo P   Amadeo Gabriela G   Martínez-Castellanos María A MA  

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20210216 2


COVID-19, caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), affects people of all ages. The virus can cause multiple systemic infections, principally in the respiratory tract, as well as microvascular damage. Ocular manifestations of COVID-19 are uncommon in adults and children. We describe ophthalmic manifestations in newborns detected by slit-lamp examination, fundus examination, and fluorescein angiography. All patients showed edema and hemorrhagic conjunctivitis; fundus e  ...[more]

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