LncRNA DNAJC3-AS1 Regulates Fatty Acid Synthase via the EGFR Pathway to Promote the Progression of Colorectal Cancer.
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ABSTRACT:
SUBMITTER: Tang Y
PROVIDER: S-EPMC7885865 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
LncRNA DNAJC3-AS1 Regulates Fatty Acid Synthase <i>via</i> the EGFR Pathway to Promote the Progression of Colorectal Cancer.
Tang Yanyan Y Tang Rui R Tang Mengtian M Huang Ping P Liao Zhiqiang Z Zhou Jumei J Zhou Lianqing L Su Min M Chen Pan P Jiang Jiarui J Hu Yingbin Y Zhou Yujuan Y Liao QianJin Q Zeng Zhaoyang Z Xiong Wei W Chen Junhong J Nie Shaolin S
Frontiers in oncology 20210202
Colorectal cancer (CRC) is one of the most common cancers worldwide. Recent studies have shown that long non-coding RNAs (lncRNAs) are involved in tumorigenesis and the development of CRC. By constructing a differential lncRNA expression profile, we screened gene chips and found that DNAJC3-AS1 was highly expressed in CRC tissues and was associated with poor prognosis in patients with CRC. Further, we proved through assays such as wound healing, colony formation, and Cell Counting Kit-8 (CCK8) t ...[more]
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