Unknown

Dataset Information

0

Recent advances in understanding cholangiocarcinoma.


ABSTRACT: The definition of cholangiocarcinoma (CCA) encompasses all tumors originating in the epithelium of the bile ducts, including the intrahepatic bile ducts (ICCA) and extrahepatic bile ducts (ECCA). The incidence of ICCA and ECCA has increased in the last few decades, and molecular advances in both entities have brought understanding of their differences and allowed treatment advances aimed at personalized therapy. In this review, we discuss recent progress in the molecular landscape of CCAs, emerging treatment biomarker-guided strategies, and future insights into the management of advanced disease.

SUBMITTER: Uson Junior PLS 

PROVIDER: S-EPMC7886064 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

altmetric image

Publications

Recent advances in understanding cholangiocarcinoma.

Uson Junior Pedro Luiz Serrano PLS   Arora Mansi M   Bogenberger James M JM   Borad Mitesh J MJ  

Faculty reviews 20201119


The definition of cholangiocarcinoma (CCA) encompasses all tumors originating in the epithelium of the bile ducts, including the intrahepatic bile ducts (ICCA) and extrahepatic bile ducts (ECCA). The incidence of ICCA and ECCA has increased in the last few decades, and molecular advances in both entities have brought understanding of their differences and allowed treatment advances aimed at personalized therapy. In this review, we discuss recent progress in the molecular landscape of CCAs, emerg  ...[more]

Similar Datasets

| S-EPMC5017284 | biostudies-other
| S-EPMC7324948 | biostudies-literature
| S-EPMC6290972 | biostudies-literature
| S-EPMC6913220 | biostudies-literature
| S-EPMC5224683 | biostudies-literature
| S-EPMC4995679 | biostudies-literature
| S-EPMC8130412 | biostudies-literature
| S-EPMC9022729 | biostudies-literature
| S-EPMC6173127 | biostudies-literature
| S-EPMC4909106 | biostudies-literature