Ontology highlight
ABSTRACT:
SUBMITTER: Hulme KD
PROVIDER: S-EPMC7886327 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
eLife 20210216
Influenza virus has a high mutation rate, such that within one host different viral variants can emerge. Evidence suggests that influenza virus variants are more prevalent in pregnant and/or obese individuals due to their impaired interferon response. We have recently shown that the non-allergic, paucigranulocytic subtype of asthma is associated with impaired type I interferon production. Here, we seek to address if this is associated with an increased emergence of influenza virus variants. Comp ...[more]