Identification of Primary and Metastatic Lung Cancer-Related lncRNAs and Potential Targeted Drugs Based on ceRNA Network.
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ABSTRACT:
SUBMITTER: Dong S
PROVIDER: S-EPMC7886985 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Identification of Primary and Metastatic Lung Cancer-Related lncRNAs and Potential Targeted Drugs Based on ceRNA Network.
Dong Siyao S Wu Cheng C Song Chengyan C Qi Baocui B Liu Lu L Xu Yan Y
Frontiers in oncology 20210203
Lung cancer metastasis is the leading cause of poor prognosis and death for patients. Long noncoding RNAs (lncRNAs) have been validated the close correlation with lung cancer metastasis, but few comprehensive analyses have reported the specific association between lncRNA and cancer metastasis, especially <i>via</i> both competing endogenous RNA (ceRNA) regulatory relationships and functional regulatory networks. Here, we constructed primary and metastatic ceRNA networks, identified 12 and 3 cand ...[more]
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