Ontology highlight
ABSTRACT:
SUBMITTER: Armanetti P
PROVIDER: S-EPMC7887578 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20201221 4
Near infrared (NIR)-resonant gold nanoparticles (AuNPs) hold great promise in cancer diagnostics and treatment. However, translating the theranostic potential of AuNPs into clinical applications still remains a challenge due to the difficulty to improve the efficiency and specificity of tumor delivery in vivo as well as the clearance from liver and spleen to avoid off target toxicity. In this study, endothelial colony forming cells (ECFCs) are exploited as vehicles to deliver AuNPs to tumors. It ...[more]