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ABSTRACT: Background
The purpose of this study was to investigate risk factors of in-hospital mortality and vascular complications after coronary artery bypass grafting (CABG), particularly the effect of different glycemic control levels on outcomes in patients with and without previous evidence of diabetes.Methods
A total of 8682 patients with and without previous diabetes undergoing CABG were categorized into strict, moderate, and liberal glucose control groups according to their mean blood glucose control level <7.8?mmol/L, 7.8 to 10.0?mmol/L, and ?10.0?mmoL/L after in-hospital CABG.Results
The patients with previous diabetes had higher rates of in-hospital mortality (1.3% vs 0.4%, P?< .001) and major complications (7.0% vs 4.8%, P?ConclusionsDiabetes status, smoking, and LDL-C levels were modifiable risk factors of both in-hospital mortality and major complications after CABG. Strict glucose control was associated with an increased risk of in-hospital mortality among patients with diabetes, whereas it reduced the risk of major complications among non-previous diabetic patients.
SUBMITTER: Chen Y
PROVIDER: S-EPMC7891320 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Chen Yanyan Y Zhang Heng H Hou Xiaopei X Li Xiaojue X Qian Xin X Feng Xinxing X Liu Shuqian S Shi Na N Zhao Wei W Hu Shengshou S Zheng Zhe Z Li Guangwei G
Journal of diabetes 20200914 3
<h4>Background</h4>The purpose of this study was to investigate risk factors of in-hospital mortality and vascular complications after coronary artery bypass grafting (CABG), particularly the effect of different glycemic control levels on outcomes in patients with and without previous evidence of diabetes.<h4>Methods</h4>A total of 8682 patients with and without previous diabetes undergoing CABG were categorized into strict, moderate, and liberal glucose control groups according to their mean bl ...[more]