Association of intraoperative hypotension with postoperative morbidity and mortality: systematic review and meta-analysis.

ABSTRACT:

Background

Intraoperative hypotension, with varying definitions in literature, may be associated with postoperative complications. The aim of this meta-analysis was to assess the association of intraoperative hypotension with postoperative morbidity and mortality.

Methods

MEDLINE, Embase and Cochrane databases were searched for studies published between January 1990 and August 2018. The primary endpoints were postoperative overall morbidity and mortality. Secondary endpoints were postoperative cardiac outcomes, acute kidney injury, stroke, delirium, surgical outcomes and combined outcomes. Subgroup analyses, sensitivity analyses and a meta-regression were performed to test the robustness of the results and to explore heterogeneity.

Results

The search identified 2931 s

SUBMITTER: Wijnberge M 

PROVIDER: S-EPMC7893468 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature