Ontology highlight
ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC7894015 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Yang Yun Y Zheng Jie J Wang Mengchao M Zhang Jin J Tian Tao T Wang Zhiheng Z Yuan Shengxian S Liu Lei L Zhu Peng P Gu Fangming F Fu Siyuan S Shan Yunfeng Y Pan Zeya Z Zhou Weiping W
Cancer science 20201213 2
Patients with hepatocellular carcinoma (HCC) are usually diagnosed at the later stages and have poor survival outcomes. New molecules are urgently needed for the prognostic predication and individual treatment. Our study showed that high levels of NQO1 expression frequently exist in HCC with an obvious cancer-specific pattern. Patients with NQO1-high tumors are significantly associated with poor survival outcomes and serve as independent predictors. Functional experiments showed that NQO1 promot ...[more]