Simulation model of disease incidence driven by diagnostic activity.
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ABSTRACT:
SUBMITTER: Westerberg M
PROVIDER: S-EPMC7894333 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Simulation model of disease incidence driven by diagnostic activity.
Westerberg Marcus M Larsson Rolf R Holmberg Lars L Stattin Pär P Garmo Hans H
Statistics in medicine 20201125 5
It is imperative to understand the effects of early detection and treatment of chronic diseases, such as prostate cancer, regarding incidence, overtreatment and mortality. Previous simulation models have emulated clinical trials, and relied on extensive assumptions on the natural history of the disease. In addition, model parameters were typically calibrated to a variety of data sources. We propose a model designed to emulate real-life scenarios of chronic disease using a proxy for the diagnosti ...[more]
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