Ontology highlight
ABSTRACT:
SUBMITTER: Dimou NL
PROVIDER: S-EPMC7894468 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Dimou Niki L NL Papadimitriou Nikos N Mariosa Daniela D Johansson Mattias M Brennan Paul P Peters Ulrike U Chanock Stephen J SJ Purdue Mark M Bishop D Timothy DT Gago-Dominquez Manuela M Giles Graham G GG Moreno Victor V Platz Elizabeth A EA Tangen Catherine M CM Wolk Alicja A Zheng Wei W Wu Xifeng X Campbell Peter T PT Giovannucci Edward E Lin Yi Y Gunter Marc J MJ Murphy Neil N
International journal of cancer 20201026 7
Obesity is considered a chronic inflammatory state characterized by continued secretion of adipokines and cytokines. Experimental and epidemiological evidence indicates that circulating adipokines may be associated with the development of obesity-related cancers, but it is unclear if these associations are causal or confounded. We examined potential causal associations of specific adipokines (adiponectin, leptin, soluble leptin receptor [sOB-R] and plasminogen activator inhibitor-1 [PAI-1]) with ...[more]