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Procyanidin B1 promotes in vitro maturation of pig oocytes by reducing oxidative stress.

ABSTRACT: Oxidative stress negatively affects the in vitro maturation (IVM) of oocytes. Procyanidin B1 (PB1) is a natural polyphenolic compound that has antioxidant properties. In this study, we investigated the effect of PB1 supplementation during IVM of porcine oocytes. Treatment with 100??M PB1 significantly increased the MII oocytes rate (p?<0.05), the parthenogenetic (PA) blastocyst rate (p?<0.01) and the total cell number in the PA blastocyst (p?

SUBMITTER: Gao W

PROVIDER: S-EPMC7894521 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Procyanidin B1 promotes in vitro maturation of pig oocytes by reducing oxidative stress.

Gao Wei W Jin Yongxun Y Hao Jindong J Huang Siyi S Wang Dongxu D Quan Fushi F Ren Wenzhi W Zhang Jiabao J Zhang Mingjun M Yu Xianfeng X

Molecular reproduction and development 20201125 1

Oxidative stress negatively affects the in vitro maturation (IVM) of oocytes. Procyanidin B1 (PB1) is a natural polyphenolic compound that has antioxidant properties. In this study, we investigated the effect of PB1 supplementation during IVM of porcine oocytes. Treatment with 100 μM PB1 significantly increased the MII oocytes rate (p <0.05), the parthenogenetic (PA) blastocyst rate (p <0.01) and the total cell number in the PA blastocyst (p < 0.01) which were cultured in regular in vitro cultur ...[more]

PMID: 33241626

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