Potential of bacteriophages as disinfectants to control of Staphylococcus aureus biofilms.

ABSTRACT:

Background

Staphylococcus aureus is the causative agent of chronic mastitis, and can form a biofilm that is difficult to completely remove once formed. Disinfectants are effective against S. aureus, but their activity is easily affected by environmental factors and they are corrosive to equipment and chemically toxic to livestock and humans. Therefore, we investigated the potential utility of a bacteriophage as a narrow-spectrum disinfectant against biofilms formed by S. aureus. In this study, we isolated and characterized bacteriophage vB_SauM_SDQ (abbreviated to SDQ) to determine its efficacy in removing S. aureus biofilms.

Results

SDQ belongs to the family Myoviridae and consists of a hexagonal head, long neck, and short tail. This phage can sterilize a 10⁹ CFU

SUBMITTER: Song J 

PROVIDER: S-EPMC7896381 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature