Ontology highlight
ABSTRACT:
SUBMITTER: Akbari V
PROVIDER: S-EPMC7898412 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Akbari Vahid V Garant Jean-Michel JM O'Neill Kieran K Pandoh Pawan P Moore Richard R Marra Marco A MA Hirst Martin M Jones Steven J M SJM
Genome biology 20210222 1
The ability of nanopore sequencing to simultaneously detect modified nucleotides while producing long reads makes it ideal for detecting and phasing allele-specific methylation. However, there is currently no complete software for detecting SNPs, phasing haplotypes, and mapping methylation to these from nanopore sequence data. Here, we present NanoMethPhase, a software tool to phase 5-methylcytosine from nanopore sequencing. We also present SNVoter, which can post-process nanopore SNV calls to i ...[more]