Ontology highlight
ABSTRACT:
SUBMITTER: Clawson BC
PROVIDER: S-EPMC7900186 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Nature communications 20210222 1
Learning-activated engram neurons play a critical role in memory recall. An untested hypothesis is that these same neurons play an instructive role in offline memory consolidation. Here we show that a visually-cued fear memory is consolidated during post-conditioning sleep in mice. We then use TRAP (targeted recombination in active populations) to genetically label or optogenetically manipulate primary visual cortex (V1) neurons responsive to the visual cue. Following fear conditioning, mice res ...[more]