Dataset Information

Attrition Bias in an Observational Study of Very Low-Energy Diet: A Cohort Study.

ABSTRACT:

Objective

Obesity treatment is plagued by attrition. Estimates of attrition bias are needed. Thus, in this study, percent change from baseline BMI at 1, 2, and 3 years following enrollment in a 2-year weight management program using a very low-energy diet was calculated. Program data were supplemented with information from medical records.

Methods

Attrition was classified as occurring early (<6 months), late (6-21 months), at program completion (22-28 months), and after program completion (>28 months). Stepwise multivariable regression examined attrition and other covariates.

Results

A total of 881 subjects had ≥3 years of follow-up. BMI decreased by a mean (SD) of 11.8 (9.2), 8.6 (9.3), and 5.2 (10.0) kg/m² at 1, 2, and 3 years after enrollment, respectively. At year 1, every 10-kg/m² increase in baseline BMI was associated with a 2% (95% CI: 1%-3%) decrease in BMI. Individuals with early attrition decreased their mean BMI by 13% (11%-15%) less than program completers and by 9% (7%-11%) at 2 years. At 3 years, there was no significant difference in BMI between individuals with early attrition and program completers. However, BMI decreased 5% (3%- 8%) more in individuals who extended participation compared with program completers.

Conclusions

Reported outcomes of weight management programs must account for program attrition.

SUBMITTER: Isaman DJM

PROVIDER: S-EPMC7902335 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Publications

Attrition Bias in an Observational Study of Very Low-Energy Diet: A Cohort Study.

Isaman Deanna J M DJM Herman William H WH Rothberg Amy E AE

Obesity (Silver Spring, Md.) 20201116 1

<h4>Objective</h4>Obesity treatment is plagued by attrition. Estimates of attrition bias are needed. Thus, in this study, percent change from baseline BMI at 1, 2, and 3 years following enrollment in a 2-year weight management program using a very low-energy diet was calculated. Program data were supplemented with information from medical records.<h4>Methods</h4>Attrition was classified as occurring early (<6 months), late (6-21 months), at program completion (22-28 months), and after program co ...[more]

PMID: 33200563

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Dataset Information

Attrition Bias in an Observational Study of Very Low-Energy Diet: A Cohort Study.

Objective

Methods

Results

Conclusions

Publications

Attrition Bias in an Observational Study of Very Low-Energy Diet: A Cohort Study.

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