Ontology highlight
ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC7902522 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Xu Xinjie X Huang Shengkang S Xiao Xinyi X Sun Qihang Q Liang Xiaoqian X Chen Sifei S Zhao Zijing Z Huo Zhaochang Z Tu Sanfang S Li Yuhua Y
Frontiers in immunology 20210210
Chimeric antigen receptor (CAR) T-cell therapy exhibits desirable and robust efficacy in patients with acute lymphoblastic leukemia (ALL). Stimulated by the revolutionized progress in the use of FDA-approved CD19 CAR T cells, novel agents with CAR designs and targets are being produced in pursuit of superior performance. However, on the path from bench to bedside, new challenges emerge. Accessibility is considered the initial barrier to the transformation of this patient-specific product into a ...[more]