Ontology highlight
ABSTRACT:
SUBMITTER: Shetty R
PROVIDER: S-EPMC7902619 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Shetty Rohit R Kumar Nimisha Rajiv NR Subramani Murali M Krishna Lekshmi L Murugeswari Ponnalagu P Matalia Himanshu H Khamar Pooja P Dadachanji Zelda V ZV Mohan Rajiv R RR Ghosh Arkasubhra A Das Debashish D
Scientific reports 20210223 1
Corneal haze post refractive surgery is prevented by mitomycin c (MMC) treatment though it can lead to corneal endothelial damage, persistent epithelial defects and necrosis of cells. Suberanilohydroxamic acid (SAHA) however has been proposed to prevent corneal haze without any adverse effects. For clinical application we have investigated the short and long term outcome of cells exposed to SAHA. Human donor cornea, cultured limbal epithelial cells, corneal rims and lenticules were incubated wit ...[more]