Ontology highlight
ABSTRACT:
SUBMITTER: Garrido-Rodriguez M
PROVIDER: S-EPMC7904194 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Garrido-Rodriguez Martín M Lopez-Lopez Daniel D Ortuno Francisco M FM Peña-Chilet María M Muñoz Eduardo E Calzado Marco A MA Dopazo Joaquin J
PLoS computational biology 20210211 2
MIGNON is a workflow for the analysis of RNA-Seq experiments, which not only efficiently manages the estimation of gene expression levels from raw sequencing reads, but also calls genomic variants present in the transcripts analyzed. Moreover, this is the first workflow that provides a framework for the integration of transcriptomic and genomic data based on a mechanistic model of signaling pathway activities that allows a detailed biological interpretation of the results, including a comprehens ...[more]