Ontology highlight
ABSTRACT:
SUBMITTER: Ewida A
PROVIDER: S-EPMC7904536 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Ewida Amr A Ahmed Rashid R Luo Anqi A Ghonim Hesham T HT Anilkumar Arayamparambil C AC
Cureus 20210125 1
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a complex group of disorders with multisystem involvement that have a wide range of biochemical and genetic defects. The earliest symptoms of MELAS typically include easy fatigability, muscle weakness, encephalopathy with stroke-like episodes, recurrent headaches and seizures. The pathogenesis of stroke-like episodes manifesting as focal deficits like acute cortical blindness is not fully understood. We present ...[more]