Ontology highlight
ABSTRACT:
SUBMITTER: Gontu A
PROVIDER: S-EPMC7904946 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Gontu Abhinay A Srinivasan Sreenidhi S Salazar Eric E Nair Meera Surendran MS Nissly Ruth H RH Greenawalt Denver D Bird Ian M IM Herzog Catherine M CM Ferrari Matthew J MJ Poojary Indira I Katani Robab R Lindner Scott E SE Minns Allen M AM Rossi Randall R Christensen Paul A PA Castillo Brian B Chen Jian J Eagar Todd N TN Yi Xin X Zhao Picheng P Leveque Christopher C Olsen Randall J RJ Bernard David W DW Gollihar Jimmy J Kuchipudi Suresh V SV Musser James M JM Kapur Vivek V
Communications biology 20210224 1
Millions of individuals who have recovered from SARS-CoV-2 infection may be eligible to participate in convalescent plasma donor programs, yet the optimal window for donating high neutralizing titer convalescent plasma for COVID-19 immunotherapy remains unknown. Here we studied the response trajectories of antibodies directed to the SARS-CoV-2 surface spike glycoprotein and in vitro SARS-CoV-2 live virus neutralizing titers (VN) in 175 convalescent donors longitudinally sampled for up to 142 day ...[more]