Ontology highlight
ABSTRACT:
SUBMITTER: Ruohtula T
PROVIDER: S-EPMC7905218 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Ruohtula Terhi T Kondrashova Anita A Lehtonen Jussi J Oikarinen Sami S Hämäläinen Anu-Maaria AM Niemelä Onni O Peet Aleksandr A Tillmann Vallo V Nieminen Janne K JK Ilonen Jorma J Knip Mikael M Vaarala Outi O Hyöty Heikki H
Frontiers in immunology 20210211
Early childhood infections have been implicated in the development of immune-mediated diseases, such as allergies, asthma, and type 1 diabetes. We set out to investigate the immunomodulatory effects of early viral infections experienced before the age of one year on the peripheral regulatory T cell population (Treg) and circulating cytokines in a birth-cohort study of Estonian and Finnish infants. We show here a temporal association of virus infection with the expression of FOXP3 in regulatory T ...[more]