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Body Mass Index and Its Change from Adolescence to Adulthood Are Closely Related to the Risk of Adult Metabolic Syndrome in China.


ABSTRACT:

Aims

To investigate the influence of body mass index (BMI) and its change from adolescence to adulthood (?BMI) on the risk of metabolic syndrome (MetS) in early adulthood.

Methods

We selected 931 students from 12 to 16 years of age in Liaoyang City, China. Ninety-three participants from 18 to 22 years of age with complete baseline data were available for follow-up after 5 years. Statistical analysis determined the relationship of MetS at follow-up with baseline BMI (BMIb), ?BMI, and follow-up BMI (BMIf).

Results

?BMI was positively correlated with the change of waist circumference (?WC), systolic blood pressure (?SBP), triglycerides (?TG), uric acid, and glycosylated hemoglobin (?HbA1c) in follow-up (p < 0.05). For every 1?kg/m2 increase in BMIb, ?BMI, and BMIf, the risk of MetS at follow-up increased 1.201-fold, 1.406-fold, and 1.579-fold, respectively. Both BMIb and ?BMI were predictive of MetS at follow-up, with prediction thresholds of 23.47?kg/m2 and 1.95?kg/m2. The participants were divided by the predicted BMIb and ?BMI threshold values into four study groups. Interestingly, the group with lower BMI but a higher increase in BMI presented the same metabolic derangements and Mets% of the group with higher BMI but lower ? BMI.

Conclusion

Both BMI of adolescence and ?BMI were predictive of MetS and cardiovascular risk factors in adulthood. Control of both variables in adolescents would be more effective in decreasing the risk of MetS in young adults than control of BMI alone.

SUBMITTER: Liu B 

PROVIDER: S-EPMC7906799 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Publications

Body Mass Index and Its Change from Adolescence to Adulthood Are Closely Related to the Risk of Adult Metabolic Syndrome in China.

Liu Bingyang B   Li Yue Y   Guo Jiamei J   Fan Yuting Y   Li Ling L   Li Ping P  

International journal of endocrinology 20210218


<h4>Aims</h4>To investigate the influence of body mass index (BMI) and its change from adolescence to adulthood (ΔBMI) on the risk of metabolic syndrome (MetS) in early adulthood.<h4>Methods</h4>We selected 931 students from 12 to 16 years of age in Liaoyang City, China. Ninety-three participants from 18 to 22 years of age with complete baseline data were available for follow-up after 5 years. Statistical analysis determined the relationship of MetS at follow-up with baseline BMI (BMI<sub>b</sub  ...[more]

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