Ontology highlight
ABSTRACT:
SUBMITTER: Metselaar PI
PROVIDER: S-EPMC7907358 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Scientific reports 20210225 1
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic disorder characterized by disabling fatigue. Several studies have sought to identify diagnostic biomarkers, with varying results. Here, we innovate this process by combining both mRNA expression and DNA methylation data. We performed recursive ensemble feature selection (REFS) on publicly available mRNA expression data in peripheral blood mononuclear cells (PBMCs) of 93 ME/CFS patients and 25 healthy controls, and found a s ...[more]