Ontology highlight
ABSTRACT:
SUBMITTER: Bresler P
PROVIDER: S-EPMC7907429 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Bresler Priscillia P Tejerina Emmanuel E Jacob Jean Marie JM Legrand Agnès A Quellec Véronique V Ezine Sophie S Peduto Lucie L Cherrier Marie M
iScience 20210207 3
Innate lymphoid cells (ILCs) have been shown to be significantly affected in the small intestine lamina propria and secondary lymphoid organs (SLOs) of conventional lymphopenic mice. How ILCs are regulated by adaptive immunity in SLOs remains unclear. In T cell-deficient mice, ILC2s are significantly increased in the mesenteric lymph nodes (MLNs) at the expense of CCR6<sup>+</sup> ILC3s, which are nonetheless increased in the peripheral lymph nodes (PLNs). Here, we show that T cells regulate lym ...[more]