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Quality of life in multiple sclerosis: The differential impact of motor and cognitive fatigue.


ABSTRACT:

Background

Multiple sclerosis is a chronic disease leading to reduced quality of life.

Objectives

To investigate whether motor and cognitive fatigue impact differently on aspects of quality of life among patients with multiple sclerosis, independently from bodily disability.

Methods

79 patients with multiple sclerosis from Aalborg University Hospital, Denmark were included in an observational, cross-sectional study. Each subject completed two separate questionnaires regarding fatigue (Fatigue Scale for Motor and Cognitive Functions and Modified Fatigue Impact Scale) and one regarding quality of life (Short Form 36). Disability was measured with the Expanded Disability Status Scale (EDSS)-scores obtained from patient records.

Results

All fatigue scores were significantly correlated to all areas of quality of life (p?ConclusionIncreased motor and cognitive fatigue lead to a differential reduction in physical and mental quality of life, independently of bodily disability. This underlines the importance of proper assessment and treatment of fatigue among patients with multiple sclerosis.

SUBMITTER: David Ruban S 

PROVIDER: S-EPMC7907948 | biostudies-literature | 2021 Jan-Mar

REPOSITORIES: biostudies-literature

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Publications

Quality of life in multiple sclerosis: The differential impact of motor and cognitive fatigue.

David Ruban Sabina S   Christina Hilt Claudia C   Petersen Thor T  

Multiple sclerosis journal - experimental, translational and clinical 20210101 1


<h4>Background</h4>Multiple sclerosis is a chronic disease leading to reduced quality of life.<h4>Objectives</h4>To investigate whether motor and cognitive fatigue impact differently on aspects of quality of life among patients with multiple sclerosis, independently from bodily disability.<h4>Methods</h4>79 patients with multiple sclerosis from Aalborg University Hospital, Denmark were included in an observational, cross-sectional study. Each subject completed two separate questionnaires regardi  ...[more]

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