Ontology highlight
ABSTRACT:
SUBMITTER: Kurek M
PROVIDER: S-EPMC7911157 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Kurek Magdalena M Åkesson Elisabet E Yoshihara Masahito M Oliver Elizabeth E Cui Yanhua Y Becker Martin M Alves-Lopes João Pedro JP Bjarnason Ragnar R Romerius Patrik P Sundin Mikael M Norén Nyström Ulrika U Langenskiöld Cecilia C Vogt Hartmut H Henningsohn Lars L Petersen Cecilia C Söder Olle O Guo Jingtao J Mitchell Rod T RT Jahnukainen Kirsi K Stukenborg Jan-Bernd JB
Cells 20210127 2
Fertility preservation for male childhood cancer survivors not yet capable of producing mature spermatozoa, relies on experimental approaches such as testicular explant culture. Although the first steps in somatic maturation can be observed in human testicular explant cultures, germ cell depletion is a common obstacle. Hence, understanding the spermatogonial stem cell (SSC) niche environment and in particular, specific components such as the seminiferous basement membrane (BM) will allow progres ...[more]