Ontology highlight
ABSTRACT:
SUBMITTER: Dupuy A
PROVIDER: S-EPMC7911484 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Dupuy Alexander A Hagimola Lejla L Mgaieth Neil S A NSA Houlahan Callum B CB Preketes-Tardiani Renee E RE Coleman Paul R PR Passam Freda H FH
Diagnostics (Basel, Switzerland) 20210129 2
Microfluidic devices have an established role in the study of platelets and coagulation factors in thrombosis, with potential diagnostic applications. However, few microfluidic devices have assessed the contribution of neutrophils to thrombus formation, despite increasing knowledge of neutrophils' importance in cardiovascular thrombosis. We describe a thromboinflammation model which uses straight channels, lined with fixed human umbilical vein endothelial cells, after treatment with tumour necro ...[more]