Sialic Acids and Their Influence on Human NK Cell Function.
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ABSTRACT:
SUBMITTER: Rosenstock P
PROVIDER: S-EPMC7911748 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
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Sialic Acids and Their Influence on Human NK Cell Function.
Rosenstock Philip P Kaufmann Thomas T
Cells 20210129 2
Sialic acids are sugars with a nine-carbon backbone, present on the surface of all cells in humans, including immune cells and their target cells, with various functions. Natural Killer (NK) cells are cells of the innate immune system, capable of killing virus-infected and tumor cells. Sialic acids can influence the interaction of NK cells with potential targets in several ways. Different NK cell receptors can bind sialic acids, leading to NK cell inhibition or activation. Moreover, NK cells hav ...[more]
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