Ontology highlight
ABSTRACT:
SUBMITTER: Luczo JM
PROVIDER: S-EPMC7911750 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Luczo Jasmina M JM Ronzulli Sydney L SL Tompkins Stephen M SM
Viruses 20210121 2
Natural killer (NK) cells are part of the innate immunity repertoire, and function in the recognition and destruction of tumorigenic and pathogen-infected cells. Engagement of NK cell activating receptors can lead to functional activation of NK cells, resulting in lysis of target cells. NK cell activating receptors specific for non-major histocompatibility complex ligands are NKp46, NKp44, NKp30, NKG2D, and CD16 (also known as FcγRIII). The natural cytotoxicity receptors (NCRs), NKp46, NKp44, an ...[more]