Ontology highlight
ABSTRACT:
SUBMITTER: Tobita Y
PROVIDER: S-EPMC7911852 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Tobita Yutaro Y Arima Takeshi T Nakano Yuji Y Uchiyama Masaaki M Shimizu Akira A Takahashi Hiroshi H
Pharmaceuticals (Basel, Switzerland) 20210125 2
The effects of each subtype-selective peroxisome proliferator activated receptor (PPAR) agonist (α, β/δ, γ) on corneal epithelial wound healing were investigated using a rat corneal alkali burn model. After the alkali burn, each PPAR agonist or vehicle ophthalmic solution was instilled topically onto the rat's cornea. Corneal epithelial healing processes were evaluated by fluorescein staining. Pathological analyses and real-time reverse transcription polymerase chain reactions were performed to ...[more]