Ontology highlight
ABSTRACT:
SUBMITTER: Junod SL
PROVIDER: S-EPMC7911914 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Junod Samuel L SL Saredy Jason J Yang Weidong W
Viruses 20210122 2
Understanding the detailed nuclear import kinetics of adeno-associated virus (AAV) through the nuclear pore complex (NPC) is essential for the application of AAV capsids as a nuclear delivery instrument as well as a target for drug development. However, a comprehensive understanding of AAV transport through the sub-micrometer NPCs in live cells calls for new techniques that can conquer the limitations of conventional fluorescence microscopy and electron microscopy. With recent technical advances ...[more]