Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC7912111 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Zhang Jack J Conly John J McClure JoAnn J Wu Kaiyu K Petri Bjӧrn B Barber Duane D Elsayed Sameer S Armstrong Glen G Zhang Kunyan K
Microorganisms 20210130 2
USA300 is a predominant and highly virulent community-associated methicillin-resistant <i>Staphylococcus aureus</i> (CA-MRSA) strain that is a leading cause of skin and soft tissue infections. We established a murine intradermal infection model capable of demonstrating dermatopathological differences between USA300 and other MRSA strains. In this model, USA300 induced dermonecrosis, uniformly presenting as extensive open lesions with a histologically documented profound inflammatory cell infiltr ...[more]