Dataset Information

Effects of Essential Oils-Based Supplement and Salmonella Infection on Gene Expression, Blood Parameters, Cecal Microbiome, and Egg Production in Laying Hens.

ABSTRACT: One of the main roles in poultry resistance to infections caused by Salmonella is attributed to host immunity and intestinal microbiota. We conducted an experiment that involved challenging Lohmann White laying hens with Salmonella Enteritidis (SE), feeding them a diet supplemented with an EOs-based phytobiotic Intebio^®. At 1 and 7 days post-inoculation, the expression profiles of eight genes related to immunity, transport of nutrients in the intestine, and metabolism were examined. Cecal microbiome composition and blood biochemical/immunological indices were also explored and egg production traits recorded. As a result, the SE challenge of laying hens and Intebio^® administration had either a suppressive or activating effect on the expression level of the studied genes (e.g., IL6 and BPIFB3), the latter echoing mammalian/human tissue-specific expression. There were also effects of the pathogen challenge and phytobiotic intake on the cecal microbiome profiles and blood biochemical/immunological parameters, including those reflecting the activity of the birds' immune systems (e.g., serum bactericidal activity, ?-lysine content, and immunoglobulin levels). Significant differences between control and experimental subgroups in egg performance traits (i.e., egg weight/number/mass) were also found. The phytobiotic administration suggested a positive effect on the welfare and productivity of poultry.

SUBMITTER: Laptev GY

PROVIDER: S-EPMC7912222 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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Effects of Essential Oils-Based Supplement and Salmonella Infection on Gene Expression, Blood Parameters, Cecal Microbiome, and Egg Production in Laying Hens.

Laptev Georgi Yu GY Yildirim Elena A EA Ilina Larisa A LA Filippova Valentina A VA Kochish Ivan I II Gorfunkel Elena P EP Dubrovin Andrei V AV Brazhnik Evgeni A EA Narushin Valeriy G VG Novikova Natalia I NI Novikova Oksana B OB Dunyashev Timur P TP Smolensky Vladimir I VI Surai Peter F PF Griffin Darren K DK Romanov Michael N MN

Animals : an open access journal from MDPI 20210201 2

One of the main roles in poultry resistance to infections caused by Salmonella is attributed to host immunity and intestinal microbiota. We conducted an experiment that involved challenging Lohmann White laying hens with Salmonella Enteritidis (SE), feeding them a diet supplemented with an EOs-based phytobiotic Intebio®. At 1 and 7 days post-inoculation, the expression profiles of eight genes related to immunity, transport of nutrients in the intestine, and metabolism we ...[more]

PMID: 33535430

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Dataset Information

Effects of Essential Oils-Based Supplement and Salmonella Infection on Gene Expression, Blood Parameters, Cecal Microbiome, and Egg Production in Laying Hens.

Publications

Effects of Essential Oils-Based Supplement and <i>Salmonella</i> Infection on Gene Expression, Blood Parameters, Cecal Microbiome, and Egg Production in Laying Hens.

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