Ontology highlight
ABSTRACT:
SUBMITTER: Aulia A
PROVIDER: S-EPMC7912522 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Aulia Annisa A Hyodo Kiwamu K Hisano Sakae S Kondo Hideki H Hillman Bradley I BI Suzuki Nobuhiro N
Biology 20210131 2
Previously, we have reported the ability of a symptomless hypovirus Cryphonectria hypovirus 4 (CHV4) of the chestnut blight fungus to facilitate stable infection by a co-infecting mycoreovirus 2 (MyRV2)-likely through the inhibitory effect of CHV4 on RNA silencing (Aulia et al., Virology, 2019). In this study, the N-terminal portion of the CHV4 polyprotein, termed p24, is identified as an autocatalytic protease capable of suppressing host antiviral RNA silencing. Using a bacterial expression sys ...[more]