Ontology highlight
ABSTRACT:
SUBMITTER: Moore CA
PROVIDER: S-EPMC7913313 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Moore Caitlyn A CA Siddiqui Zain Z Carney Griffin J GJ Naaldijk Yahaira Y Guiro Khadidiatou K Ferrer Alejandra I AI Sherman Lauren S LS Guvendiren Murat M Kumar Vivek A VA Rameshwar Pranela P
Polymers 20210203 4
Translational medicine requires facile experimental systems to replicate the dynamic biological systems of diseases. Drug approval continues to lag, partly due to incongruencies in the research pipeline that traditionally involve 2D models, which could be improved with 3D models. The bone marrow (BM) poses challenges to harvest as an intact organ, making it difficult to study disease processes such as breast cancer (BC) survival in BM, and to effective evaluation of drug response in BM. Furtherm ...[more]