Ontology highlight
ABSTRACT:
SUBMITTER: Harisna AH
PROVIDER: S-EPMC7914023 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Harisna Azza Hanif AH Nurdiansyah Rizky R Syaifie Putri Hawa PH Nugroho Dwi Wahyu DW Saputro Kurniawan Eko KE Firdayani Prakoso Chandra Dwi CD Rochman Nurul Taufiqu NT Maulana Nurwenda Novan NN Noviyanto Alfian A Mardliyati Etik E
Biochemistry and biophysics reports 20210227
Docking analysis of propolis's natural compound was successfully performed against SARS-CoV-2 main protease (Mpro) and spike protein subunit 2 (S2). Initially, the propolis's protein was screened using chromatography analysis and successfully identified 22 compounds in the propolis. Four compounds were further investigated, i.e., neoblavaisoflavone, methylophiopogonone A, 3'-Methoxydaidzin, and genistin. The binding affinity of 3'-Methoxydaidzin was -7.7 kcal/mol, which is similar to nelfinavir ...[more]