A Pilot Study of Bioenergetic Marker Relationships in Gulf War Illness: Phosphocreatine Recovery vs. Citric Acid Cycle Intermediates.
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ABSTRACT:
SUBMITTER: Golomb BA
PROVIDER: S-EPMC7914405 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
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A Pilot Study of Bioenergetic Marker Relationships in Gulf War Illness: Phosphocreatine Recovery vs. Citric Acid Cycle Intermediates.
Golomb Beatrice A BA Koslik Hayley J HJ Han Jun Hee JH Preger Guida Anna Helena AH Hamilton Gavin G Kelley Richard I RI
International journal of environmental research and public health 20210209 4
Impaired bioenergetics have been reported in veterans with Gulf War illness (VGWIs), including prolonged post-exercise recovery of phosphocreatine (PCr-R) assessed with <sup>31</sup>Phosphorus magnetic resonance spectroscopy. The citric acid cycle (CAC) is considered the most important metabolic pathway for supplying energy, with relationships among CAC markers reported to shift in some but not all impaired bioenergetic settings. We sought to assess relations of CAC markers to one another and to ...[more]
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