Ontology highlight
ABSTRACT:
SUBMITTER: Glombik K
PROVIDER: S-EPMC7915890 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Głombik Katarzyna K Detka Jan J Bobula Bartosz B Bąk Joanna J Kusek Magdalena M Tokarski Krzysztof K Budziszewska Bogusława B
International journal of molecular sciences 20210205 4
The role that thyroid hormone deficiency plays in depression and synaptic plasticity in adults has only begun to be elucidated. This paper analyzes the possible link between depression and hypothyroidism in cognitive function alterations, using Wistar-Kyoto (WKY-an animal model of depression) rats and control Wistar rats under standard and thyroid hormone deficiency conditions (propylthiouracil administration-PTU). A weakening of memory processes in the WKY rats is shown behaviorally, and in the ...[more]