Ontology highlight
ABSTRACT:
SUBMITTER: De Gaetano F
PROVIDER: S-EPMC7920302 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
De Gaetano Federica F Cristiano Maria Chiara MC Venuti Valentina V Crupi Vincenza V Majolino Domenico D Paladini Giuseppe G Acri Giuseppe G Testagrossa Barbara B Irrera Alessia A Paolino Donatella D Tommasini Silvana S Ventura Cinzia Anna CA Stancanelli Rosanna R
Molecules (Basel, Switzerland) 20210216 4
This study was aimed at preparing and characterizing solid lipid nanoparticles loading rutin (RT-SLNs) for the treatment of oxidative stress-induced diseases. Phospholipon 80H<sup>®</sup> as a solid lipid and Polysorbate 80 as surfactant were used for the SLNs preparation, using the solvent emulsification/diffusion method. We obtained spherical RT-SLNs with low sizes, ranging from 40 to 60 nm (hydrodynamic radius) for the SLNs prepared starting from 2% and 5% (<i>w/w</i>) theoretical amount. All ...[more]