PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis.

ABSTRACT: Single-cell RNA-Sequencing (scRNA-Seq) has improved our understanding of individual cell types in the human placenta. However, placental scRNA-Seq data is not readily accessible when trying to understand how expression patterns in model systems correspond to those from first trimester human placenta. Therefore, we developed PlacentaCellEnrich, a tool that takes a gene set as input, and then reports if the input set is enriched for genes with placenta cell-specific expression patterns, based on human placenta scRNA-Seq data. The PlacentaCellEnrich tool is freely available at https://placentacellenrich.gdcb.iastate.edu/ for non-profit academic use under the MIT license.

SUBMITTER: Jain A 

PROVIDER: S-EPMC7920947 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature