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Knowledge Representation for Multi-Scale Physiology Route Modeling.


ABSTRACT: We present a framework for the topological and semantic assembly of multiscale physiology route maps. The framework, called ApiNATOMY, consists of a knowledge representation (KR) model and a set of knowledge management (KM) tools. Using examples of ApiNATOMY route maps, we present a KR format that is suitable for the analysis and visualization by KM tools. The conceptual KR model provides a simple method for physiology experts to capture process interactions among anatomical entities. In this paper, we outline the KR model, modeling format, and the KM procedures to translate concise abstraction-based specifications into fully instantiated models of physiology processes.

SUBMITTER: Kokash N 

PROVIDER: S-EPMC7921311 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Knowledge Representation for Multi-Scale Physiology Route Modeling.

Kokash Natallia N   de Bono Bernard B  

Frontiers in neuroinformatics 20210216


We present a framework for the topological and semantic assembly of multiscale physiology route maps. The framework, called ApiNATOMY, consists of a knowledge representation (KR) model and a set of knowledge management (KM) tools. Using examples of ApiNATOMY route maps, we present a KR format that is suitable for the analysis and visualization by KM tools. The conceptual KR model provides a simple method for physiology experts to capture process interactions among anatomical entities. In this pa  ...[more]

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