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Demonstration of Green Solvent Performance on O,S,N-Heterocycles Synthesis: Metal-Free Click Chemistry and Buchwald-Hartwig Coupling.

ABSTRACT: The development of new and greener approaches to organic synthesis has been a trend in recent years. Continuing the latest publications of our team, in this work, we demonstrate the efficiency of three solvents: eucalyptol (1,8-cineole), cyclopentyl methyl ether (CPME), and 2-methyltetrahydrofuran (2-MeTHF) for the synthesis of O,S,N-heterocyclic compounds.

SUBMITTER: Campos JF 

PROVIDER: S-EPMC7922032 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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Demonstration of Green Solvent Performance on O,S,N-Heterocycles Synthesis: Metal-Free Click Chemistry and Buchwald-Hartwig Coupling.

Campos Joana F JF   Cailler Manon M   Claudel Remi R   Prot Benjamin B   Besson Thierry T   Berteina-Raboin Sabine S  

Molecules (Basel, Switzerland) 20210218 4

The development of new and greener approaches to organic synthesis has been a trend in recent years. Continuing the latest publications of our team, in this work, we demonstrate the efficiency of three solvents: eucalyptol (1,8-cineole), cyclopentyl methyl ether (CPME), and 2-methyltetrahydrofuran (2-MeTHF) for the synthesis of O,S,N-heterocyclic compounds. ...[more]

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