Pulmonary Fibrosis in COVID-19 Recovered Patients: Problem and Potential Management.
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ABSTRACT:
SUBMITTER: Kayarat B
PROVIDER: S-EPMC7922461 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Pulmonary Fibrosis in COVID-19 Recovered Patients: Problem and Potential Management.
Kayarat Bhavana B Khanna Puneet P Sarkar Soumya S
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20210201 2
<b>How to cite this article:</b> B, Khanna P, Sarkar S. Pulmonary Fibrosis in COVID-19 Recovered Patients: Problem and Potential Management. Indian J Crit Care Med 2021;25(2):242-244. ...[more]
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Project description:BackgroundMyocardial injury (MI) can be detected during the acute phase of Coronavirus disease 19 (COVID-19) and is associated with a dismal prognosis. Recent imaging studies described the persistence of cardiac abnormalities after the recovery. The aim of the study was to investigate the spectrum of cardiac abnormalities at mid-term follow-up in patients recovered from COVID-19 using clinical assessment, laboratory tests, and imaging evaluation with comprehensive echocardiography.MethodsThis is an observational, cross-sectional study assessing an unselected cohort of consecutive patients recovered from COVID-19. MI was defined by elevated plasma levels of high sensitive troponin T (hsTnT). At the follow-up, a complete examination including echocardiography was performed.ResultsThe 123 patients included were divided into two groups according to the presence of MI during hospitalization: group A (without MI) and group B (with MI). After a median of 85 days, group B patients were more frequently symptomatic for dyspnea and had significantly higher values of hsTnT and N-Terminal prohormone of Brain Natriuretic Peptide (NT-proBNP), compared to Group A. No differences between the two groups in left nor right ventricle dimension and ejection fraction were found. However, in group B a significant reduction of mean left ventricle global longitudinal strain was observed (-15.7±.7 vs -18.1± .3 in group A, p < 0.001), together with higher frequency of impaired diastolic function and higher values of pulmonary pressure.ConclusionsIn patients recovered from COVID-19, echocardiography with speckle-tracking analysis may be an useful imaging tool to identify subclinical myocardial dysfunction and potentially guide management strategies.
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