Ontology highlight
ABSTRACT:
SUBMITTER: Gutierrez GJ
PROVIDER: S-EPMC7923546 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Gutierrez Gabrielle J GJ Rieke Fred F Shea-Brown Eric T ET
Proceedings of the National Academy of Sciences of the United States of America 20210201 8
Neural circuits are structured with layers of converging and diverging connectivity and selectivity-inducing nonlinearities at neurons and synapses. These components have the potential to hamper an accurate encoding of the circuit inputs. Past computational studies have optimized the nonlinearities of single neurons, or connection weights in networks, to maximize encoded information, but have not grappled with the simultaneous impact of convergent circuit structure and nonlinear response functio ...[more]