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ABSTRACT: Background
The serum hemoglobin (Hb) level is closely related to adverse clinical outcomes. However, data on the association of Hb levels with subclinical atherosclerosis beyond metabolic abnormalities are limited.Methods
This study evaluated the association among serum Hb level, metabolic syndrome (MetS), and the risk of carotid plaque formation in asymptomatic adults without a history of major adverse clinical events.Results
A total of 2560 participants (mean age: 60?±?8 years, 32.9% men) were stratified into four groups based on Hb quartiles, as follows: ??12.8 g/dL (group I), 12.9-13.6 g/dL (group II), 13.7-14.5 g/dL (group III), and ??14.6 g/dL (group IV). The overall prevalence of MetS and carotid plaque was 37.2% and 33.4%, respectively. The prevalence of MetS increased with increasing Hb level (group I: 27.4% vs. group II: 35.9% vs. group III: 42.6% vs. group IV: 44.1%, p?ConclusionSerum Hb level is associated with the risk of carotid plaque beyond MetS and its components in a relatively healthy adult population.
SUBMITTER: Choi Y
PROVIDER: S-EPMC7923602 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Choi Yunsuk Y Won Ki-Bum KB Kang Hyeon Hui HH Change Hyuk-Jae HJ
BMC cardiovascular disorders 20210302 1
<h4>Background</h4>The serum hemoglobin (Hb) level is closely related to adverse clinical outcomes. However, data on the association of Hb levels with subclinical atherosclerosis beyond metabolic abnormalities are limited.<h4>Methods</h4>This study evaluated the association among serum Hb level, metabolic syndrome (MetS), and the risk of carotid plaque formation in asymptomatic adults without a history of major adverse clinical events.<h4>Results</h4>A total of 2560 participants (mean age: 60 ± ...[more]