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Association of serum hemoglobin level with the risk of carotid plaque beyond metabolic abnormalities among asymptomatic adults without major adverse clinical events: a cross-sectional cohort study.


ABSTRACT:

Background

The serum hemoglobin (Hb) level is closely related to adverse clinical outcomes. However, data on the association of Hb levels with subclinical atherosclerosis beyond metabolic abnormalities are limited.

Methods

This study evaluated the association among serum Hb level, metabolic syndrome (MetS), and the risk of carotid plaque formation in asymptomatic adults without a history of major adverse clinical events.

Results

A total of 2560 participants (mean age: 60?±?8 years, 32.9% men) were stratified into four groups based on Hb quartiles, as follows: ??12.8 g/dL (group I), 12.9-13.6 g/dL (group II), 13.7-14.5 g/dL (group III), and ??14.6 g/dL (group IV). The overall prevalence of MetS and carotid plaque was 37.2% and 33.4%, respectively. The prevalence of MetS increased with increasing Hb level (group I: 27.4% vs. group II: 35.9% vs. group III: 42.6% vs. group IV: 44.1%, p?ConclusionSerum Hb level is associated with the risk of carotid plaque beyond MetS and its components in a relatively healthy adult population.

SUBMITTER: Choi Y 

PROVIDER: S-EPMC7923602 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Publications

Association of serum hemoglobin level with the risk of carotid plaque beyond metabolic abnormalities among asymptomatic adults without major adverse clinical events: a cross-sectional cohort study.

Choi Yunsuk Y   Won Ki-Bum KB   Kang Hyeon Hui HH   Change Hyuk-Jae HJ  

BMC cardiovascular disorders 20210302 1


<h4>Background</h4>The serum hemoglobin (Hb) level is closely related to adverse clinical outcomes. However, data on the association of Hb levels with subclinical atherosclerosis beyond metabolic abnormalities are limited.<h4>Methods</h4>This study evaluated the association among serum Hb level, metabolic syndrome (MetS), and the risk of carotid plaque formation in asymptomatic adults without a history of major adverse clinical events.<h4>Results</h4>A total of 2560 participants (mean age: 60 ±   ...[more]

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