Ontology highlight
ABSTRACT:
SUBMITTER: Raue R
PROVIDER: S-EPMC7926641 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Raue Rebecca R Frank Ann-Christin AC Syed Shahzad Nawaz SN Brüne Bernhard B
International journal of molecular sciences 20210223 4
The tumor-microenvironment (TME) is an amalgamation of various factors derived from malignant cells and infiltrating host cells, including cells of the immune system. One of the important factors of the TME is microRNAs (miRs) that regulate target gene expression at a post transcriptional level. MiRs have been found to be dysregulated in tumor as well as in stromal cells and they emerged as important regulators of tumorigenesis. In fact, miRs regulate almost all hallmarks of cancer, thus making ...[more]