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Short and long term exposure to air pollution increases the risk of ischemic heart disease.

ABSTRACT: Previous studies have suggested an increased risk of ischemic heart disease related to air pollution. This study aimed to explore both the short-term and long-term effects of air pollutants on the risk of ischemic heart disease after adjusting for meteorological factors. The Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2013 was used. Overall, 2155 participants with ischemic heart disease and 8620 control participants were analyzed. The meteorological data and air pollution data, including SO₂ (ppm), NO₂ (ppm), O₃ (ppm), CO (ppm), and particulate matter (PM)₁₀ (?g/m³), were analyzed using conditional logistic regression. Subgroup analyses were performed according to age, sex, income, and region of residence. One-month exposure to SO₂ was related to 1.36-fold higher odds for ischemic heart disease (95% confidence interval [95% CI] 1.06-1.75). One-year exposure to SO₂, O₃, and PM₁₀ was associated with 1.58- (95% CI 1.01-2.47), 1.53- (95% CI 1.27-1.84), and 1.14 (95% CI 1.02-1.26)-fold higher odds for ischemic heart disease. In subgroup analyses, the???60-year-old group, men, individuals with low income, and urban groups demonstrated higher odds associated with 1-month exposure to SO₂. Short-term exposure to SO₂ and long-term exposure to SO_2, O₃, and PM₁₀ were related to ischemic heart disease.

SUBMITTER: Kim SY

PROVIDER: S-EPMC7930275 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Short and long term exposure to air pollution increases the risk of ischemic heart disease.

Kim So Young SY Kim Sang Hoon SH Wee Jee Hye JH Min Chanyang C Han Sang-Min SM Kim Seungdo S Choi Hyo Geun HG

Scientific reports 20210303 1

Previous studies have suggested an increased risk of ischemic heart disease related to air pollution. This study aimed to explore both the short-term and long-term effects of air pollutants on the risk of ischemic heart disease after adjusting for meteorological factors. The Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2013 was used. Overall, 2155 participants with ischemic heart disease and 8620 control participants were analyzed. The meteorological data and air ...[more]

PMID: 33658616

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Project description:BACKGROUND:Long-term exposure to particulate matter (PM) in ambient air has been associated with cardiovascular mortality, but few studies have considered incident disease in relation to PM from different sources. OBJECTIVES:We aimed to study associations between long-term exposure to different types of PM and sources, and incident ischemic heart disease (IHD) and stroke in three Swedish cities. METHODS:Based on detailed emission databases, monitoring data, and high-resolution dispersion models, we calculated source contributions to PM with aerodynamic diameter ?10?m (PM10), PM with aerodynamic diameter ?2.5?m (PM2.5), and black carbon (BC) from road wear, traffic exhaust, residential heating, and other sources in Gothenburg, Stockholm, and Umeå. Registry data for participants from four cohorts were used to obtain incidence of IHD and stroke for first hospitalization or death. We constructed time windows of exposure for same-year, 1- to 5-y, and 6- to 10-y averages preceding incidence from annual averages at residential addresses. Risk estimates were based on random effects meta-analyses of cohort-specific Cox proportional hazard models. RESULTS:We observed 5,166 and 3,119 incident IHD and stroke cases, respectively, in 114,758 participants. Overall, few consistent associations were observed between the different air pollution measures and IHD or stroke incidence. However, same-year levels of ambient locally emitted BC (range: 0.01-4.6??g/m3) were associated with a 4.0% higher risk of incident stroke per interquartile range (IQR), 0.30??g/m3 [95% confidence interval (CI): 0.04, 7.8]. This association was primarily related to BC from traffic exhaust. PM10 (range: 4.4-52??g/m3) and PM2.5 (range: 2.9-22??g/m3) were not associated with stroke. Associations with incident IHD were observed only for PM2.5 exposure from residential heating. DISCUSSION:Few consistent associations were observed between different particulate components and IHD or stroke. However, long-term residential exposure to locally emitted BC from traffic exhaust was associated with stroke incidence. The comparatively low exposure levels may have contributed to the paucity of associations. https://doi.org/10.1289/EHP4757.

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Short and long term exposure to air pollution increases the risk of ischemic heart disease.

Publications

Short and long term exposure to air pollution increases the risk of ischemic heart disease.

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